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Design and Construction of Low-Cost Scientific Instrumentation for Neurophysiology and Environmental Research

Our research focuses on the design and development of affordable scientific instruments based on programmable boards such as Arduino Uno, Arduino Nano, and STM32 Nucleo platforms. By leveraging these flexible and accessible technologies, we aim to lower the barrier to advanced experimental tools, making high-quality research more widely attainable.

Over the past years, we have engineered two custom devices that have been scientifically validated and described in international peer-reviewed journals. The first is a low-cost electrical stimulator designed for studies on benthic organisms, such as foraminifera, with the goal of investigating the effects of underwater electrical pollution on marine ecosystems. The second is an instrument for measuring transepithelial electrical resistance (TEER) in cell cultures, a widely used assay to evaluate barrier integrity in biological tissues. Importantly, the TEER device can be easily adapted for use with both conventional Transwell systems and custom organ-on-chip platforms, which we design and fabricate in-house using biocompatible resins and advanced 3D printing techniques.

These tools demonstrate that reliable, precise, and reproducible measurements can be achieved without the prohibitive costs of conventional commercial equipment. By developing and disseminating open and adaptable hardware solutions, our work contributes both to neurophysiological research and to the broader scientific community, offering innovative methodologies to address environmental and biomedical challenges.

Design and Construction of Low-Cost Scientific Instrumentation for Neurophysiology and Environmental Research
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